The Structural Evolution of Outer Membrane Beta Barrels

Monday, February 4, 2019 - 4:00pm

Outer membrane proteins (OMPs) are the proteins in the surface of Gram-negative bacteria. These proteins have diverse functions but a single topology: the β-barrel. I will discuss the evolutionary pathways and origins of this topology. The mechanisms of diversification have implications for antibiotic resistance, repeat protein biogenesis, and the nucleation of outermembrane protein folding.   

Prof. Joanna Slusky - U. Kansas
Gavin King