Prof. King addresses fundamental problems in biophysics via precision single-molecule measurement apparatus. Specifically, he is developing and implementing a unique ultrastable atomic force microscope (AFM) to elucidate the structure, structural energetics, and conformational fluctuations of membrane proteins. A central question is: How does the dynamic structure of these proteins influence their function? An ultrastable AFM complements traditional characterization techniques by providing an atomically precise means to address this question in physiologically relevant conditions.

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